Squalene in fruiting bodies of true mushrooms changes in the process of vegetation
DOI:
https://doi.org/10.6092/issn.2531-7342/19781Keywords:
squalene, aphyllophoroid fungi, Tyromyces chioneus, Mucidula múcida, lipophilic extractsAbstract
The paper presents the results of the search for raw sources of squalene among real mushrooms. Lipophilic extracts obtained from fruiting bodies of 22 species were analyzed, 21 of which belonged to the class of Agaricomycetes of the orders Pezizales, Polyporales, Cantharellales, Russulales, Boletales, and one species to the class of Pezizomycetes of the order Pezizales. It was established that the content of squalene in lipophilic extracts from the fruiting bodies of Tyromyces chioneus, Fomitopsis betulina, Pleurotus ostreatus and Postia stiptica can exceed the content of squalene in fatty oil from the seeds of Amaranthus caudatus. However, the mass of the lipophilic extract obtained from the dried fruiting bodies of these mushrooms is insignificant. Also, the content of squalene in fruiting bodies at different stages of development, as shown by studies conducted on aphyllophoroid mushrooms Tyromyces chioneus, Laetiporus sulphureus, Pleurotus ostreatus, Fomitopsis betulina, Mucidula múcida, decreases as the fruiting bodies of these mushrooms ripen. At the same time, the yield of lipophilic extract from the fruiting bodies of M. múcida, is abnormally high, 9‒15% and increases during their ripening and, although the squalene content in them decreases as the mushrooms grow, this decrease is much smaller than in other mushrooms.
References
Aghajani H, Bari E, Bahmani M, Humar M, Ali M, Ghanbary MAT, Nicholas DD, Zahedian E (2018) Influence of relative humidity and temperature on cultivation of Pleurotus species. Maderas - Ciencia y tecnología 20(4):571‒578. https://doi.org/10.4067/S0718-221X2018005004501
Asgharpour F, Moghadamnia AA, Alizadeh Y, Kazemi S (2020) Chemical Composition and antibacterial activity of hexane extract of Lycoperdon pyriforme. South African Journal of Botany 131:195‒199. https://doi.org/10.1016/j.sajb.2020.01.044
Baraniak J, Kania-Dobrowolska M (2022) The dual nature of amaranth — Functional food and potential medicine. Foods 11(4):618. https://doi.org/10.3390/foods11040618
Daou M, Yassine B, Wikee S, Record E, Duprat F, Bertrand E, Faulds CB (2019) Pycnoporus cinnabarinus glyoxal oxidases display differential catalytic efficiencies on 5-hydroxymethylfurfural and its oxidized derivatives. Fungal biology and biotechnology 6:1‒15. https://doi.org/10.1186/s40694-019-0067-8
Garuba T, Abdukkareem KA, Ibrahim IA, Oyebamiji OI, Shoyooye OA, Ajibade TD (2017) Influence of substrates on the nutritional quality of Pleurotus pulmonarius and Pleurotus ostreatus. Ceylon Journal of Science 46(1):67‒74. https://doi.org/10.4038/cjs.v46i1.7419
Hamidi M, Okoro OV, Milan PB, Khalili MR, Samadian H, Nie L, Shavandi A (2022) Fungal exopolysaccharides: properties, sources, modifications, and biomedical applications. Carbohydrate polymers 284:119152. https://doi.org/10.1016/j.carbpol.2022.119152
He HP, Cai Y, Sun M, Corke H (2002) Extraction and purification of squalene from Amaranthus Grain. Journal of Agricultural and Food Chemistry 50:368‒372. https://doi.org/10.1021/jf010918p
Huang ZR, Lin YK, Fang JY (2009) Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. Molecules 14(1):540–554. https://doi.org/10.3390/molecules14010540
Hultberg M, Ahrens L, Golovko O (2020) Use of lignocellulosic substrate colonized by oyster mushroom (Pleurotus ostreatus) for removal of organic micropollutants from water. Journal of Environmental Management 272:111087. https://doi.org/10.1016/j.jenvman.2020.111087
Kim EH, Woodruff MC, Grigoryan L, Maier B, Lee SH, Manda P, Cortese M, Natrajan MS, Ravindran R, Ma H, Merad M, Gitlin AD, Mocarski ES, Jacob J, Pulendran B (2020) Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway. eLife 9:e52687. https://doi.org/10.7554/eLife.52687
Kobayashi T, Oguro M, Akiba M, Taki H., Kitajima H, Ishihara H (2020) Mushroom yield of cultivated shiitake (Lentinula edodes) and fungal communities in logs. Journal of Forest Research 25(4):269‒275. https://doi.org/10.1080/13416979.2020.1759886
Korabel IM, Panchak LV, Zyn AR, Antonyuk VO (2022) Obtaining of biologically active substances from Amaranthus caudatus L. seeds in one technological cycle. Biomedical chromatography 36(8):e5386. https://doi.org/10.1002/bmc.5386
Kuo M (2022) Mushroomexpert.com homepage. https://www.mushroomexpert.com/index.html
Kurchenko VP, Sushinskaya NV, Kiseleva IS, Ermoshin AA (2022) Biologically active substances in fruit bodies of wood decomposing fungi. AIP Conference Proceedings 2390:030045. https://doi.org/10.1063/5.0069253
Landínez-Torres AY, Pérez Fagua C, López ACS, Deaquiz Oyola YA, Girometta CE (2021) Pruning wastes from fruit trees as a substrate for Pleurotus ostreatus. Acta Mycologica 56(1). https://doi.org/10.5586/am.568
Mendes A, Azevedo-Silva J, Fernandes JC (2022) From sharks to yeasts: squalene in the development of vaccine adjuvants. Pharmaceuticals 15(3):265. https://doi.org/10.3390/ph15030265
Popa O, Băbeanu NE, Popa I, Niță S, Dinu-Parvu CE (2015) Methods for obtaining and determination of squalene from natural sources. BioMed Research International ID:367202. https://doi.org/10.1155/2015/367202
Regis MAJ, Geösel A (2024) Cultivation of Auricularia species: a review of the history, health benefits, principles, practices, environmental conditions, research methods, and recent trends. Sydowia 76:21. https://doi.org/10.12905/0380.sydowia76-2024-0021
Safonov MA (2003) The structure of communities of xylotrophic fungi. Ekaterinburg: Ural Branch of the Russian Academy of Sciences 269
Tsimidou M (2010) Squalene and tocopherols in olive oil: importance and methods of analysis. In: Olives and Oliv Oil in Health and Disease Prevention (Preedy VR, Watson RR, eds). Academic Press, London, UK, pp 561–567. https://doi.org/10.1016/B978-0-12-374420-3.00061-9
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Copyright (c) 2025 Ivan M. Korabel, Lidiia V. Panchak, Alina R. Zyn, Volodymyr O. Antonyuk
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